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Harnessing the Power of Bispecific Antibodies
October 14, 2021 @ 10:00 AM – 11:30 AM
Creative Biolabs has invited Dr. Archana Thakur and Dr. Luca Varani to walk us through how they utilize the power of bsAbs to 1) arm “headless CAR T cells” and serially kill tumor targets and 2) neutralize wild-type SARS-CoV-2 and its variants and suppress viral escape.
New insights you will learn through the following two key topics we will discuss in this webinar:
1. Bispecific Antibody Armed Metabolically Enhanced Headless CAR T Cells
The design of bsAb armed metabolically enhanced headless CAR T cells (hCART)
The generation of bsAb armed metabolically enhanced hCART
The efficacy of bsAb armed metabolically enhanced hCART in preclinical studies
2. Bispecific Antibody Protects from SARS-CoV-2 Variants of Concern and Prevents Viral Escape in Mice
The development of the bispecific IgG1-like molecule (CoV-X2)
CoV-X2 neutralizes wild-type SARS-CoV-2 and its variants in preclinical studies
CoV-X2 protects mice from infection and suppresses viral escape