CASSS DC Area Scientific Discussion Group

IBBR 9600 Gudelsky Drive, Rockville, MD

Pure Knowledge: Improving Downstream Processing by Deciphering Separation Mechanisms Speakers: Haibin Luo, AstraZeneca Formation of transient highly-charged mAb clusters strengthens interactions with host cell proteins and results in poor clearance of host cell proteins during downstream processing Kamiyar Rezvani, AstraZeneca Leveraging Light Chain Binding Avidity for Control of Mispaired Byproducts During Capture of Bispecific Antibodies