Delfi Diagnostics’ AI-based blood test detects 80% of early-stage lung cancer cases, study finds

These days, cancer-spotting liquid biopsy offerings are a dime a dozen, with everyone from Grail to Guardant throwing their hats in the ring and cancer-screening blood test developers making up three of the top five highest-funded medtech companies in 2020.

But while Delfi Diagnostics’ goal of creating a more accurate and affordable method to detect early-stage cancers reflects the aims of its many competitors in the space, it’s taking a different approach to get there.

That approach—which looks for millions of possible abnormalities in the breakages of a patient’s cell-free DNA molecules, rather than looking for cancer in genetic mutations or methylation groups—seems to have paid off.

According to a study of just under 800 patients that was published Friday in the journal Nature Communications, Delfi’s test was able to spot about 90% of lung cancer cases, including 80% of stage 1 cases. The results were validated by low-dose CT (LDCT) scans, which are recommended for high-risk patients ages 50 and up to screen for lung cancer but are rarely performed.

Click here to read more via Fierce Biotech.