Cartesian Therapeutics Establishes New Corporate Headquarters and State-of-the-Art mRNA Cell Therapy cGMP Manufacturing Facility in Frederick, Maryland 

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Cartesian Therapeutics Establishes New Corporate Headquarters and State-of-the-Art mRNA Cell Therapy cGMP Manufacturing Facility in Frederick, Maryland New facility expected to support expanded cGMP manufacturing of clinical and commercial supply [….]

And the Finalists Are… Meet Your BioHealth Capital Region 2023 Annual Awards Finalists

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We are thrilled to announce the finalists for BioBuzz’s 2023 Annual Awards for the BioHealth Capital Region (Maryland, Washington, DC, Virginia).

Weekly Quick Hits (BioHealth Capital Region) – Week of April 24, 2023

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Weekly Quick Hits (BioHealth Capital Region) – Week of April 24, 2023 By Sarah Ellinwood, Alex Keown, and Mark TerryApril 28, 2023 Funding, Awards and Collaborations Quest Diagnostics Acquires Haystack [….]

Cartesian Therapeutics Kicks Off Phase IIb study of rCAR-T in Autoimmune Disease

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The Gaithersburg-based company dosed the first patient with Descartes-08, the company’s first-in-class, RNA-engineered chimeric antigen receptor T-cell therapy (rCAR-T). The placebo-controlled study, the first such trial of its kind, is expected to build on the recently-completed Phase IIa program. The study is expected to enroll 30 myasthenia patients, 15 of whom will receive a six-week course of Descartes-08 and 15 who will receive placebo.

Top Stem Cell Companies Supported by the Maryland Stem Cell Research Fund

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Since its inception, MSCRF has invested over $170 million in over 500 projects to accelerate stem cell research, commercialization, and cures. With a 2023 fiscal year budget of $20.5M, MSCRF offers six funding opportunities to scientists and companies in the areas of clinical trials, discovery, commercialization, validation, launch, and post-doctoral fellowships. The fund has supported the creation and growth of many stem cell companies since launching the Accelerating Cures initiative in 2017.

Moving To An Allogeneic RNA Cell Therapy Program With Cartesian Therapeutics Dr. Metin Kurtoglu

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Cartesian Therapeutics’ Dr. Metin Kurtoglu joins Cell & Gene: The Podcast to explain their autologous RNA cell therapies, Descartes-08 for Myasthenia Gravis and Descartes-11 for multiple myeloma. He also sheds light on Descartes-25, their allogeneic RNA cell therapy, and the reasons for the move to “off-the-shelf.” Hear why the future of RNA cell therapy is not confined to rare and fatal diseases and subscribe so you never miss an episode!

Cartesian, BD and REGENXBIO’s Ken Mills Take Home Top Honors at MTC’s Industry Awards Celebration

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The Maryland Tech Council, the largest technology and life science trade association in the state, announced the winners of its 2022 Industry Awards Thursday at the Bethesda North Marriott Hotel & Conference Center. The event, which honored companies, executives, students, and educators in 15 categories, marked the first in-person gathering for the Industry Awards Celebration since 2019. 

Cartesian Therapeutics Doses Patient with First Allogeneic RNA Cell Therapy for Multiple Myeloma

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Cartesian Therapeutics, a fully integrated clinical-stage biotechnology company pioneering RNA cell therapy in and beyond oncology, today announced that it has dosed the first patient in a Phase 1/2a multicenter clinical study evaluating Descartes-25 in patients with multiple myeloma.  To the company’s knowledge, Descartes-25 is the first off-the-shelf RNA cell therapy to enter clinical trials for any cancer and marks the company’s fifth FDA Investigational New Drug (IND) allowance in five years.  Descartes-25 is produced at Cartesian’s wholly owned cGMP manufacturing facility with the company’s proprietary RNA Armory® cell manufacturing platform.  This platform now includes an internally developed, Part 1271-compliant Master Cell Bank of human umbilical cord Mesenchymal Stem Cells (MSC) that was used to engineer Descartes-25.

Meet Your 2021 BioBuzz Award Winners

Orange banner with photos of people, with text saying "2nd Annual BioBuzz Awards - Presenting Your Winners"
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Today, we are excited to announce the winners of our 2nd Annual BioBuzz Awards. The BioBuzz Awards are a celebration of the exciting and groundbreaking work being done by the BioHealth Capital Region (BHCR) life science community and the individuals that make innovation happen across Maryland, Virginia, and Washington, D.C.