Weekly Quick Hits (Greater Philly) – Week of April 3, 2023

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Weekly Quick Hits (Greater Philly) – Week of April 3, 2023 By Mark Terry, Alex Keown, and Sarah EllinwoodApril 7, 2023 Funding, Awards and Collaborations Jefferson U to Expand Jefferson [….]

Weekly Quick Hits (Greater Philly) – Week of March 27, 2023

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Weekly Quick Hits (Greater Philly) – Week of March 27, 2023 By Mark Terry, Alex Keown, and Sarah EllinwoodMarch 31, 2023 A special thank you to everyone who came out [….]

Incyte Announces Data from Two LIMBER Studies Evaluating Combination Treatments in Patients with Myelofibrosis (MF) Presented at ASH 2022

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Incyte (Nasdaq:INCY) today announced new data from two of its LIMBER (Leadership In MPNs and GVHD BEyond Ruxolitinib) trials evaluating monotherapy and combination strategies using ruxolitinib (Jakafi®) with parsaclisib, its investigational phosphatidylinositol 3-kinase delta (PI3Kδ) inhibitor, and INCB00928 (zilurgisertib), its activin receptor-like kinase (ALK2) inhibitor, in patients with myelofibrosis (MF). These Phase 2 and Phase 1/2 trials (Abstract #236 and Abstract #1714, respectively) were presented at the 64th American Society of Hematology (ASH) Annual Meeting, held December 10-13, 2022, in New Orleans and virtually1,2.

5 Questions With Michelle Kinder, Ph.D., Director of Translational Sciences at Incyte

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I was attracted to Incyte for its immuno-oncology pipeline. When I first joined Incyte as a Scientific Director, Immuno-Oncology in U.S. Medical Affairs, I had the opportunity to support the growing pipeline, explore novel biology and enable our therapeutics into clinical practice.

Incyte Announces Agreement to Acquire Medicxi-backed Villaris Therapeutics and Auremolimab (VM6), an Anti-IL-15Rβ Monoclonal Antibody

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Incyte (NASDAQ:INCY) today announced that the Company has entered into an agreement to acquire Villaris Therapeutics, an asset-centric biopharmaceutical company seeded by Medicxi and focused on the development of novel antibody therapeutics for vitiligo. Its lead asset, auremolimab (VM6), an anti-IL-15Rβ monoclonal antibody (mAb), is expected to enter clinical development in 2023.

Incyte Announces Positive CHMP Opinion for Capmatinib (Tabrecta®) for the Treatment of METex14 Advanced Non-Small Cell Lung Cancer

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Incyte (Nasdaq:INCY) today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency’s (EMA) has issued a positive opinion that recommends granting marketing authorization for capmatinib (Tabrecta®) as a monotherapy for the treatment of adults with advanced non-small cell lung cancer (NSCLC) harboring alterations leading to mesenchymalepithelial-transition factor gene (MET) exon 14 (METex14) skipping who require systemic therapy following prior treatment with immunotherapy and/or platinum-based chemotherapy.